The shooting occurred about 11:50 p.m. Tuesday in the 10000 block of Santa Cruz Road, near West Drive, according to the Desert Hot Springs Police Department.
The two victims, whose names were not released, were taken to an area hospital, one in critical condition and the other in stable condition. One of them died in the hospital, while the other was treated and released.
Police arrested a 17-year-old boy, whose name was also not released, within 12 hours of the shooting, and he was later charged with murder, police said.
No motive in the shooting was released, nor was any additional information.