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The clinical features and lab results of MIS-C were similar to those seen in Kawasaki disease, the authors noted, which causes inflammation in the blood vessels’ walls.

In the current group of patients, imaging patterns revealed airway inflammation, rapidly progressive pulmonary edema, coronary artery aneurysms and extensive abdominal inflammatory changes within the right “iliac fossa.” Each child also came back with abnormal white blood cell counts.

Among the 35 who underwent a chest x-ray, 19 came back abnormal, most commonly showing bronchial wall thickening. On chest CT, most showed basal consolidation, or part of the lung filling with fluid. Collapsed lung with pleural effusions or buildup of fluid in the outer membranes of the lungs was also prevalent.

Abdominal ultrasound findings included inflammatory changes within the right iliac fossa, with mesenteric fat stranding, lymphadenopathy, and bowel wall thickening, as well as free fluid in the pelvis, the authors wrote.

Further testing performed across a larger number of patients from multiple institutions is required, Hameed noted.

“As pediatric radiologists, we were interested in the emerging pattern of imaging findings that we observed in these children,” Hameed added. “Our intention is to bring these findings to the attention of the wider radiological community.”

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